Biological age measures the body’s functional state rather than the number of years since birth. This value can be higher or lower than chronological age depending on genetics, lifestyle, stress, and environmental exposures. Advances in science have made it possible to estimate biological age using at-home test kits, allowing individuals to track changes over time.

How Biological Age is Measured

• Epigenetic Clocks: Models like Horvath, GrimAge, and DunedinPACE analyze DNA methylation to estimate biological age.
• Glycan Profiling: Evaluates immune system glycans to assess immune age.
• Whole Genome Sequencing: Provides trait and health-related data for a broader view.
• Telomere Length: Measures chromosome end caps, but is less reliable as a standalone marker.

Key Factors When Comparing Test Kits

• Sample type (blood, saliva, or cheek swab)
• Biomarkers analyzed
• Report depth and clarity
• Access to app or coaching support
• Eligibility for HSA/FSA
• Accuracy based on markers analyzed and validation

Before Taking a Test

• Verify the method is peer-reviewed.
• Review privacy policies for data handling.
• Understand limitations: these are not diagnostic tools.
• Consult a qualified health professional for interpretation.

References